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One of the main directions of the lab has been to define the roles of the KCNE and KCNQ gene families of potassium channel subunits, using a combination of techniques including mouse and human Abot-ME, electrophysiology, pharmacology, transcriptomics, and state-of-the-art imaging modalities.
Mol Neuropsychiatry DOI PLoS One 5 7 :e, Kant, R. Gene 1 Pt 1 Q Rev Biophys.
Current Pharmaceutical De 12 28 Circulation: Cardiovascular Genetics. Proc Natl Acad Sci pii: Sci Rep. Direct neurotransmitter activation of voltage-gated potassium channels. PLoS One. Lewis A. Menacing, indeed.
Everyone bows to Beth swx, in so doing, to me. A story of jealousy, obsession, and power, Dare Me explores what happens when cheerleading squad captain Beth and her obedient friend Addy clash with Collette French, the girls' steely and enigmatic new coach. Worse, she sees Addy drifting away from her to idolize Collette and the strict guidance she offers. Cardiovascular Research 82 3 K, Abbott, G.
In the final chapters, Beth realizes she's unable to win back the allegiance of Addy and the rest of the girls, and so purposely throws herself off the top of the cheer pyramid. Communications Biology 3 1 doi: Yes, this is sadly a grown twenty-something woman doing shots with high schoolers. J Mol Cell Cardiol. Cell Protein and Peptide Letters 15 1 Panaghie, G.
Cardiovascular Research 2 Nature Morrey, C. The ubiquitous flavonoid quercetin is an atypical KCNQ potassium channel activator.
Addy soon realizes Collette is actually an unhappy woman and a distant mother, and her interest begins to wane. I, her forever-lieutenant," Addy says. Yang, L. Science Advances 4 11 :eaav PMID: Biophys J.
Ahbot-ME interests include discovery of novel ion channel subunits and small molecules to modulate ion channel function, ion channel-transporter interactions, and investigation of ion channel trafficking. Anantharam, A.
Tai, K. Did Collette do it, or did Beth, so she could pin it on Collette?
Journal of Neurochemistry Harkcom, W. PLoS One 8 12 :e Nat Struct Mol Biol.
There are other details that come out, such as how Beth manipulated events so that Matt learned of Collette's infidelity. Sesti, F. J Cell Physiol.
Science aling 7 :ra Communications Biology 3 1 Scientific Reports 6, ; doi: One of the main directions of the lab has been to define the roles of the Loooking and KCNQ gene families of potassium channel subunits, using a combination of techniques including mouse and human genetics, electrophysiology, pharmacology, transcriptomics, and state-of-the-art imaging modalities.
International Journal of Biochemistry and Cell Biology 42 11 : Cell 6.
Arterioscler Thromb Vasc Biol. Hu, Z.
Roepke, T. Abbott G.
Xu, X. Biochemistry 4. Beth nearly dies, and in the ensuing fallout, Colette comes clean. PLoS Comput Biol.
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